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13/02/2004
CAMBIO distributes Red/ET Kits in UK & Ireland
Gene Bridges Announces Distribution Agreement with CAMBIO Ltd., UK, for Red/ET Recombination KitsDresden, Germany: Gene Bridges GmbH announced today, that CAMBIO Ltd., Cambridge, UK, has agreed to distribute Gene Bridges’ Red/ET Recombineering Kits in the United Kingdom & Ireland. We are very pleased that a distribution organization like CAMBIO, with such a strong market presence and reputation throughout United Kingdom has agreed to distribute our Red/ET Recombineering Kits says Gary Stevens, CEO of Gene Bridges. Red/ET Recombination, also known as ET cloning or Lambda-mediated cloning, allows DNA constructs to be designed and created without size or site restrictions. The agreement includes the distribution of BAC Modification Kit, BAC Counter-Selection Kit, and BAC Subcloning Kit to non-commercial, research organisations. Commercial companies require a license from Gene Bridges.
CAMBIO sees the Red/ET kits as an ideal complement to their range of BAC libraries. Together they represent the key resources necessary for researchers to produce transgenic models with unprecedented ease. Now investigators can easily select and quickly obtain the BAC genomic sequence paired with the Red/ET kits for rapid production of transgenic constructs rather than labouring through the time-consuming process of subcloning and ligations. The Red/ET product line further extends CAMBIO’s portfolio of products that expand investigators access to tools for systems biology.
About Red/ET Technology
Red/ET Recombineering is a novel DNA Engineering technology and which represents a breakthrough in DNA cloning and mutagenesis with regard to size, precise manipulation and modification of DNA molecules: Red/ET Recombination enables the cloning of much larger DNA sequences. Traditional cloning technologies are limited to sequences approaching 20 kilo bases (kb), with Red/ET sequences of well over 200 kb can be cloned. Cloning with Red/ET Recombination is much more precise than in vitro processes. This in vivo technology uses the endogenous proofreading and repair mechanisms of the bacterium cell and therefore avoids PCR derived in vitro mutagenesis. Red/ET allows precise modifications at any chosen position of the DNA molecule. Insertions, deletions or point mutations can be performed at any point of the molecule since Red/ET works independent of inconvenient restriction sites. Red/ET makes DNA engineering simple and faster because the cloning of the target DNA is a one step procedure. BAC modifications can be performed in 2 weeks with Red/ET versus 3 months using conventional methods.
About Gene Bridges
Gene Bridges GmbH is a self-funded, biotech company which develops innovative DNA engineering technologies. Gene Bridges commercializes its exclusive rights of the patented Red/ET Recombineering technology worldwide by DNA services, licenses and products. The company was founded in 2000 as a spin-off of the European Molecular Biology
Laboratory (EMBL) and moved to Dresden in 2001. The management team includes Prof. A. Francis Stewart, PhD, and Youming Zhang, PhD, the inventors of Red/ET Recombination, and Gary Stevens, a business economist.
About Cambio
The Cambio trademark has been active for over 20 years and the company provide one of the most flexible and comprehensive sources for the molecular biologist today. As well as being exclusive UK distributor for EPICENTRE, Glen Research, Mobio, Minerva Biolabs GmbH, Bioventures, Open Biosystems, LigoChem and Princeton Separations, Cambio supplies its range of StarFISH™ chromosome paints worldwide.
For further information about Cambio Ltd please contact:
Cambio Ltd
Dr Peter Dean, Managing Director
The Irwin Centre
Scotland Road, Dry Drayton
Cambridge CB3 8AR
UK
Phone: +44 (0) 1954 210200
Fax: +44 (0) 1954 210300
